Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease.
Molecular Metabolism(2016)
Abstract
•A new model of Raptor (mTORC1) loss in adipose tissue is described.•Young fat Raptor KO mice have normal WAT mass.•Fat Raptor KO mice progressively develop lipodystrophy and metabolic disease.•Fat Raptor KO mice resist obesity but develop severe hepatomegaly.
MoreTranslated text
Key words
mTORC1,Raptor,Rapamycin,Lipodystrophy,Obesity,White Adipose Tissue (WAT)
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined