Downregulation of microRNA-216b contributes to glioma cell growth and migration by promoting AEG-1-mediated signaling.
Biomedicine & Pharmacotherapy（2018）
Abstract
•miR-216b is decreased in glioma tissues and cell lines.•miR-216b inhibits glioma cell proliferation and migration.•miR-216b targets AEG-1 3′-UTR and inhibits AEG-1 expression.•miR-216b exerts antitumor function by targeting AEG-1.
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Key words
AEG-1,miRNAs,miR-216b,NF-κB,3′-UTR,HIV,CCK-8,RT-qPCR,FBS
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