Fas/FasL interaction mediates imbalanced cytokine/cytotoxicity responses of iNKT cells against Jurkat cells.
Molecular Immunology(2018)
摘要
•iNKT cells exhibited imbalanced cytokine/cytotoxicity responses against Jurkat cells.•The imbalanced iNKT cell responses were CD1d dependent and relied mostly on Fas/FasL interaction.•Elevated CD1d levels and defects of iNKT cells were found in T-cell lymphoma patients.•Exogenous IL-2 helped to overcome the defects of iNKT cells from T lymphoma patients.
更多查看译文
关键词
iNKT,FasL,α-GalCer,APC
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要