Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology

Steven M. Walker,Laura A. Knight,Andrena M. McCavigan,Gemma E. Logan,Viktor Berge,Amir Sherif,Hardev Pandha,Anne Y. Warren,Catherine Davidson, Adam Uprichard,Jaine K. Blayney,Bethanie Price,Gera L. Jellema, Christopher J. Steele,Aud Svindland,Simon S. McDade, Christopher G. Eden,Chris Foster,Ian G. Mills,David E. Neal

European Urology（2017）

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摘要

We have identified a distinct molecular subgroup of primary prostate cancers with metastatic potential at presentation; a prospective biomarker assay to detect the group demonstrates significant performance for prediction of biochemical relapse and metastatic recurrence post surgery in independent validation sets.

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关键词

Prostate cancer,Prognostic,Recurrence,Progression,Metastatic assay

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