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Photodynamic therapy corrects abnormal cancer-associated gene expression observed in actinic keratosis lesions and induces a remodeling effect in photodamaged skin

Florence Joly,Sophie Deret,Bastien Gamboa,Corinne Menigot,Paul Fogel,Carine Mounier,Pascale Reiniche, Farzaneh Sidou,Jérome Aubert,John Lear,Anthony A. Fryer,Francesca Zolezzi,Johannes J. Voegel

Journal of Dermatological Science（2018）

Cited 9|Views26
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Abstract
•MAL-PDT corrects abnormally expressed cancer-associated genes in actinic keratosis.•MAL-PDT normalizes cell cycle-related genes in actinic keratosis.•MAL-PDT at gene expression level indicates a remodeling effect on photodamaged skin.
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AK,DEG,L,PL,ECM,MAL,NSE,NTF,FDR,OTR,PDT,SCC,UVR
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