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Transarterial chemoembolization as a substitute to radiofrequency ablation for treating Barcelona Clinic Liver Cancer stage 0/A hepatocellular carcinoma.

Oncotarget(2018)

Cited 8|Views31
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Abstract
BACKGROUND AND AIM:Transarterial chemoembolization (TACE) is the standard procedure for treating Barcelona clinic liver cancer (BCLC) stage B hepatocellular carcinoma (HCC). However, it is often carried out in the treatment of BCLC stage 0/A HCC for various reasons. This study aimed to elucidate the prognosis for BCLC stage 0/A HCC patients treated with TACE or with radiofrequency ablation (RFA). MATERIALS AND METHODS:The prognosis of 242 BCLC stage 0/A HCC patients within Milan criteria who underwent initially TACE or RFA were retrospectively analyzed using propensity score matching analysis. RESULTS:The analyses of baseline patient characteristics revealed that the maximum tumor size and the proportion of BCLC stage A patients were significantly higher in patients treated with TACE than in those treated with RFA ( PPPPPPPCONCLUSION:TACE can substitute RFA at least in some patients with BCLC 0/A HCC.
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Key words
Barcelona Clinic Liver Cancer (BCLC) staging,hepatocellular carcinoma,propensity score matching,radiofrequency ablation,transarterial chemoembolization
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