Inhibitory effects of tetramethylpyrazine on pain transmission of trigeminal neuralgia in CCI-ION rats

Wei Xiong,Mengxia Tan,Lingkun He,Xiaoyan Ou,Youhong Jin,Guo Yang,Liping Huang,Yulin Shen,Shu Guan,Changshui Xu,Guilin Li,Shuangmei Liu,Hong Xu,Shangdong Liang,Yun Gao

Brain Research Bulletin（2017）

引用 27|浏览9

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摘要

•Activated P2X3 receptor in TG aggravated pain of TN.•TMP inhibited P2X3 expression of TG.•TMP inhibited ATP currents in HEK293 cells transfected with P2X3.•TMP relieved hyperalgesia of CCI-ION rats.

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关键词

Trigeminal neuralgia,P2X3,receptor,Trigeminal ganglion,CCI-ION rats

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