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Proteome analysis of the potential serum biomarkers for chronic benzene poisoning.

Zhimin Zhang,Peimao Li,Dafeng Lin,Dianpeng Wang,Yanfang Zhang

Environmental Toxicology and Pharmacology（2018）

Cited 13|Views28
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Abstract
•We analyzed the differentially expressed proteins by using 2D-DIGE and MALDI-TOF-MS.•Identification of 10 abnormal differentially expressed proteins caused by CBP.•APOA1, a1-AT and Complement C3 were up-regulated in CBP and were validated.•Oxidative stress and inflammation may help to elucidate the mechanism of CBP.
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CBP,2D-DIGE,MALDI-TOF-MS,DTT,Tris,CHCA,IEF,CHAPS,IPG,SDS-PAGE
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