Antibody persistence and booster response 68 months after vaccination at 2-10 years of age with one dose of MenACWY-TT conjugate vaccine.

Markus Knuf,Klaus Helm,Devayani Kolhe,Marie Van Der Wielen,Yaela Baine

Vaccine（2018）

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摘要

Antibody persistence (rSBA titers ≥ 1:8) for serogroups A, W and Y was observed in more than 50.0% of the children 68 M after receiving one dose of MenACWY-TT; for MenC, antibody persistence was observed in more than one third of MenACWY-TT and more than half of MenC-CRM recipients. Vaccination with a booster dose of MenACWY-TT induced robust immune responses for all serogroups.

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关键词

AEs,ATP,CIs,GI,GMTs,hSBA,IMD,M,MenB,MenC,MenACWY-TT,MenC-CRM,NOCI,rSBA,SAEs,TT,TVC

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Antibody persistence and booster response 68 months after vaccination at 2-10 years of age with one dose of MenACWY-TT conjugate vaccine.

Antibody persistence and booster response 68 months after vaccination at 2-10 years of age with one dose of MenACWY-TT conjugate vaccine.