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The secondary prevention of stroke according to cytochrome P450 2C19 genotype in patients with acute large-artery atherosclerosis stroke.

Xingyang Yi, Jing Lin,Ju Zhou, Yanfeng Wang,Ruyue Huang,Chun Wang

Oncotarget（2018）

Cited 9|Views2
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Abstract
Among IS patients treated with clopidogrel, carriers of a reduced-function allele had a significantly higher rate of adverse vascular events than did noncarriers. It should avoid prescribing clopidogrel to these patients with known polymorphisms.
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Key words
CYP2C19 polymorphism,aspirin,clopidogrel,ischemic stroke,outcomes
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