High salt intake increases plasma trimethylamine N-oxide (TMAO) concentration and produces gut dysbiosis in rats.

Klaudia Bielinska,Marek Radkowski,Marta Grochowska,Karol Perlejewski,Tomasz Huc,Kinga Jaworska,Daisuke Motooka,Shota Nakamura,Marcin Ufnal

Nutrition（2018）

引用 47|浏览10

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摘要

•Increased plasma trimethylamine N-oxide (a bacteria metabolite) is a cardiovascular risk marker.•High salt intake was found to increase plasma trimethylamine N-oxide in rats.•High salt intake altered gut bacteria composition.•High-salt diet may affect interplay between gut bacteria and host homeostasis.

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关键词

High salt intake,Trimethylamine N-oxide,Gut bacteria,Gut-blood barrier,Cardiovascular marker

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