Evidence to Support Monitoring of Vedolizumab Trough Concentrations in Patients With Inflammatory Bowel Diseases.

Erwin Dreesen,Bram Verstockt,Sumin Bian,Magali de Bruyn,Griet Compernolle,Sophie Tops,Maja Noman,Gert Van Assche,Marc Ferrante,Ann Gils,Séverine Vermeire

Clinical Gastroenterology and Hepatology（2018）

引用 124|浏览14

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摘要

In a retrospective study of 179 patients with CD or UC, we observed a correlation between vedolizumab exposure and response. These findings support monitoring of vedolizumab trough concentrations to predict patients' outcome.

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关键词

Monoclonal Antibody,Integrin,Pharmacokinetics,Therapeutic Drug Monitoring

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