Association of K6.2 gene rs5219 variation with type 2 diabetes: A meta-analysis of 21,464 individuals.

Dong-Dong Wang,Xiao Chen,Yang Yang,Chen-Xu Liu

Primary Care Diabetes（2018）

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摘要

•Allelic genetic model demonstrated rs5219 K-allele was relevant to T2DM risk in Caucasian and East Asian.•Recessive genetic model indicated rs5219 KK genotype was related to T2DM risk in Caucasian, East Asian, South Asian, and North African.•Dominant genetic model certified rs5219 EE genotype was opposite association with T2DM risk in Caucasian.

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关键词

rs5219,Gene polymorphism,Type 2 diabetes mellitus,Meta-analysis

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