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Supratherapeutic concentrations of cilostazol inhibits β-amyloid oligomerization in vitro.

Hidenobu Shozawa,Tatsunori Oguchi,Mayumi Tsuji,Satoshi Yano,Yuji Kiuchi,Kenjiro Ono

Neuroscience Letters（2018）

Cited 11|Views5
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Abstract
•Aβ oligomers are potential neurotoxic mediators in Alzheimer's disease.•We examined the effects of cilostazol (CSZ) on Aβ oligomerization in vitro.•CSZ inhibited Aβ oligomerization, suggesting therapeutic potential.
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Aβ,AD,APP,APS,αS,CREB,CSZ,DMTs,EM,ERK,GST,LMW,low-n,MAPK,MCI,Nox,PDE3,PICUP,ROS,Ru(bpy),SDS,SDS-PAGE,ThT
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