comparLow arsenic concentrations impair memory in rat offpring exposed during pregnancy and lactation: Role of α7 nicotinic receptor, glutamate and oxidative stress.
NeuroToxicology（2018）
Abstract
•Exposure to arsenic during development impairs memory in female offspring.•Exposure to arsenic decreases the expression of α7-AChR in hippocampus.•Low arsenic levels cause oxidative damage in whole brain and hippocampus.•Exposure to arsenic increases glutamate levels that may produce excitotoxicity.
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Key words
Arsenic,α7-nicotinic receptor,Oxidative stress,Glutamate,Female rats
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