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Differential effects of natural Curcumin and chemically modified curcumin on inflammation and bone resorption in model of experimental periodontitis.

Fabiana Almeida Curylofo-Zotti,Muna S Elburki, Priscilla Aparecida Oliveira,Paulo Sérgio Cerri,Leandro Alves Santos,Hsi-Ming Lee,Francis Johnson,Lorne M Golub,Carlos Rossa,Morgana Rodrigues Guimarães-Stabili

Archives of Oral Biology（2018）

Cited 37|Views15
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Abstract
•CMC2.24 and Curcumin showed inhibitory effect on inflammation by different mechanisms.•Curcumin significantly reduced the number of apoptotic cells in the gingival tissues.•CMC2.24 attenuated inflammatory bone resorption.
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Key words
Bone resorption,Chemically modified curcumin (CMC2.24),Periodontal disease,Lipopolysaccharide,Inflammation
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