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Prognostic Impact of Tumor Mutation Burden in Patients with Completely Resected Non-Small Cell Lung Cancer: Brief Report.

Yuki Owada-Ozaki,Satoshi Muto,Hironori Takagi,Takuya Inoue,Yuzuru Watanabe,Mitsuro Fukuhara,Takumi Yamaura,Naoyuki Okabe,Yuki Matsumura,Takeo Hasegawa,Jun Ohsugi,Mika Hoshino,Yutaka Shio,Hideaki Nanamiya,Jun-Ichi Imai,Takao Isogai,Shinya Watanabe,Hiroyuki Suzuki

Journal of Thoracic Oncology（2018）

Cited 119|Views34
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Abstract
High TMB in NSCLC is a poor prognostic factor. If high TMB is a predictor of the efficacy of immune checkpoint inhibitors, postoperative adjuvant therapy with immune checkpoint inhibitors may contribute to improvement of recurrence and OS.
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Key words
Tumor mutation burden,NSCLC,Prognosis,Immune-checkpoint inhibitor
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