Efficient production of recombinant adeno-associated viral vector, serotype DJ/8, carrying the GFP gene.

Haruo Hashimoto,Tomoko Mizushima,Tsuyoshi Chijiwa,Masato Nakamura,Hiroshi Suemizu

Virus Research（2017）

引用 9|浏览20

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摘要

•AAV, Serotype DJ/8 produced by the combination of lipofectamine and iodixanol produces is an efficient yield.•AAV, Serotype DJ/8 carrying GFP gene is produced without alteration of the characteristics of protein expression and AAV gene transduction.•The AAV-DJ/8-GFP vector could transduce to human and murine hepatocyte-derived cell lines.

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关键词

AAV,GFP,serotype DJ/8,Hepatocytes

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