Placental Growth Factor informed management of suspected pre-eclampsia or fetal growth restriction: The MAPPLE cohort study.

Andrew Sharp,Lucy C Chappell,Gustaaf Dekker,Sanja Pelletier,Yves Garnier,Onur Zeren,Katharina M Hillerer,Thorsten Fischer,Paul T Seed, Mark Turner,Andrew H Shennan,Zarko Alfirevic

Pregnancy Hypertension（2018）

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摘要

•We report PlGF-led management of pregnant women as part of routine clinical care.•We compared our revealed PlGF cohort to a previous cohort with concealed PlGF results.•Revealed PlGF leads to earlier delivery by 1.4 weeks.•Revealed PlGF leads to fewer perinatal deaths and babies <3rd centile at birth.•Revealed PlGF increased neonatal morbidity, predominantly due to respiratory causes.

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关键词

Placental Growth Factor,Pre-eclampsia,Pregnancy outcome,Small for gestational age fetus,Stillbirth

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