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A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory.

Natalia Paez Arango,Lauren Brusco,Kenna R Mills Shaw,Ken Chen,Agda Karina Eterovic,Vijaykumar Holla,Amber Johnson,Beate Litzenburger,Yekaterina B Khotskaya,Nora Sanchez,Ann Bailey,Xiaofeng Zheng,Chacha Horombe,Scott Kopetz,Carol J Farhangfar,Mark Routbort,Russell Broaddus,Elmer V Bernstam,John Mendelsohn,Gordon B Mills,Funda Meric-Bernstam

ANNALS OF SURGICAL ONCOLOGY（2017）

Cited 15|Views107
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Abstract
Expanded cancer gene sequencing identifies more actionable genomic alterations. The option of CLIA validating research results can provide alternative targets for personalized cancer therapy.
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Key words
CLIA,clinical trial,genomics,precision medicine,somatic mutation
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