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Fetal cell-free DNA fraction in maternal plasma for the prediction of hypertensive disorders of pregnancy.

Nobuhiro Suzumori,Akihiko Sekizawa,Takeshi Ebara,Osamu Samura,Aiko Sasaki,Rina Akaishi,Seiji Wada,Haruka Hamanoue,Fumiki Hirahara, Haruna Izumi,Hideaki Sawai,Hiroaki Nakamura,Takahiro Yamada,Kiyonori Miura,Hideaki Masuzaki,Takahiro Yamashita,Takashi Okai,Yoshimasa Kamei,Akira Namba,Jun Murotsuki,Tomohiro Tanemoto,Akimune Fukushima,Kazufumi Haino,Shinya Tairaku,Keiichi Matsubara,Kazutoshi Maeda,Takashi Kaji,Masanobu Ogawa,Hisao Osada,Haruki Nishizawa,Yoko Okamoto,Takeshi Kanagawa,Aiko Kakigano,Michihiro Kitagawa,Masaki Ogawa,Shunichiro Izumi,Yukiko Katagiri,Naoki Takeshita,Yasuyo Kasai,Katsuhiko Naruse,Reiko Neki,Hisashi Masuyama,Maki Hyodo,Yukie Kawano,Takashi Ohba,Kiyotake Ichizuka,Takeshi Nagamatsu,Atsushi Watanabe,Nahoko Shirato,Junko Yotsumoto,Miyuki Nishiyama,Tatsuko Hirose,Haruhiko Sago

European Journal of Obstetrics & Gynecology and Reproductive Biology（2018）

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摘要
A low fetal fraction on NIPT might be correlated with future HDP. However, predicting HDP during early pregnancy in women with a low fetal fraction might be difficult.
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关键词
Cell-free DNA,Fetal fraction,HDP,NIPT,Prenatal diagnosis
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