Functional magnetic resonance imaging response as an early biomarker of cognitive decline in elderly patients with metabolic syndrome.

Nadia Shigaeff,Edson Amaro,Fabio G M Franco,Alessandro F Jacinto, Gabriela Chiochetta,Maysa S Cendoroglo,Vanessa A Citero

Archives of Gerontology and Geriatrics（2017）

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摘要

•The fMRI BOLD response was reduced for elderly individuals with MetS.•Compensatory strategy of the brain in MetS participants.•Use of cognitive reserve in the subjects of the MetS group.•Early biomarker of the development of cognitive impairment of elderly with MetS.

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关键词

Metabolic syndrome,Elderly,Biomarker,Neuropsychological assessment,Cognitive impairment,Functional magnetic resonance

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