Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

Seyed Yahya Anvar,Guy Allard,Elizabeth Tseng,Gloria M. Sheynkman,Eleonora de Klerk,Martijn Vermaat,Raymund H. Yin,Hans E. Johansson,Yavuz Ariyurek,Johan T. den Dunnen, Stephen W. Turner,Peter A. C. ‘t Hoen

Genome Biology（2018）

引用 0|浏览5

暂无评分

摘要

The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the interdependence of transcription initiation, splicing and polyadenylation events on single mRNA molecules by full-length mRNA sequencing.

查看译文

关键词

Full-length mRNA Sequences,mRNA Processing Events,Polyadenylation Site (PASs),Alternative TSSs,PacBio Data

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要