Early life trauma: An exploratory study of effects on OXTR and NR3C1 gene expression and nurturing self-efficacy in mothers of infants.

International Journal of Psychophysiology(2019)

Cited 9|Views13
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Abstract
•OXTR mRNA was increased in mothers of infants vs. no-infant controls.•Mother who experienced early life trauma had lower OXTR mRNA than mothers with no early trauma and lower NR3C1 mRNA than no-infant controls.•Mothers with depression had lower NR3C1 mRNA than non-depressed mothers.•Mothers who experienced early life trauma evaluated their support networks more negatively than mothers without early life trauma.
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Key words
Oxytocin,Glucocorticoid,Gene expression,Early childhood trauma,Maternal behavior,Social support
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