Bleeding and Thrombotic Outcomes Following Perioperative Interruption of Direct Oral Anticoagulants in Patients with Prior Venous Thromboembolic Disease

Unlabelled BoxEssentials•Studies evaluating the procedural interruption of direct oral anticoagulants (DOACs) are lacking.•We conducted a study of the interruption of DOACs for prior venous thromboembolic disease (VTE).•The post‐operative risks of recurrent VTE and major bleeding are low in this patient population.•A scheme based on half‐life and procedure‐related bleeding appears safe and efficacious.