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Toll-like Receptor 3 Modulates the Behavioral Effects of Cocaine in Mice.

Journal of neuroinflammation(2018)

Cited 31|Views29
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Abstract
The nucleus accumbens in the midbrain dopamine limbic system plays a key role in cocaine addiction. Toll-like receptors (TLRs) are important pattern-recognition receptors (PPRs) in the innate immune system that are also involved in drug dependence; however, the detailed mechanism is largely unknown.
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Key words
Cocaine,TLR3,Drug addiction,NF-κB
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