Estrogen receptor β activation within dorsal raphe nucleus reverses anxiety-like behavior induced by food restriction in female rats.

Glenda Viggiano Campos,Sylvana Rendeiro de Noronha,Aline Arlindo de Souza,Paulo Marcelo Lima,Aline Rezende Abreu,Deoclecio Chianca-Jr,Rodrigo Cunha de Menezes

Behavioural Brain Research（2019）

Cited 12|Views31

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Abstract

•Food restriction induces anxiety-like behavior in female rats.•Estradiol intra-DRN in FR animals has an anxiolytic effect.•ERβ activation in DRN neurons is involved in the control of anxiety response.•Panic-like behavior is not altered by food restriction.

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Key words

Food restriction,Estrogen,Anxiety,Dorsal raphe nucleus,ERβ

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