Protective effect of compound Danshen (Salvia miltiorrhiza) dripping pills alone and in combination with carbamazepine on kainic acid-induced temporal lobe epilepsy and cognitive impairment in rats.
Pharmaceutical biology（2018）
Abstract
These findings support the use of CDDP as an adjuvant drug for the treatment of TLE and cognitive deficit. Its mechanism might be related to an anti-apoptosis effect and up-regulation of GDNF.
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Key words
Intractable epilepsy,anti-apoptosis,antiepileptic drugs,glial cell line-derived neurotrophic factor,hippocampal CA3 area,traditional Chinese medicine
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