A prospective, randomized, comparative study of intravenous alone and combined intravenous and intraarticular administration of tranexamic acid in primary total knee replacement.

Paolo Adravanti, Eleonora Di Salvo,Giuseppe Calafiore,Sebastiano Vasta,Aldo Ampollini,Michele Attilio Rosa

Arthroplasty Today（2018）

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摘要

This study reinforces evidence that, as compared to IV TXA alone, combined IV and IA administration of TXA has a synergic effect, leading to higher postoperative Hb levels without influencing drug safety in TKA patients.

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关键词

Postoperative blood loss,Total knee arthroplasty,Tranexamic acid,Postoperative hemoglobin,Intravenous,Intraarticular

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