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BRD4 Inhibition is Synthetic Lethal with PARP Inhibitors Through the Induction of Homologous Recombination Deficiency.

Chaoyang Sun,Jun Yin,Yong Fang,Jian Chen,Kang Jin Jeong,Xiaohua Chen,Christopher P. Vellano,Zhenlin Ju, Wei Zhao,Dong Zhang,Yiling Lu,Funda Meric-Bernstam,Timothy A. Yap,Maureen Hattersley,Mark J. O'Connor,Huawei Chen,Stephen Fawell,Shiaw-Yih Lin,Guang Peng,Gordon B. Mills

Cancer Cell（2018）

Cited 259|Views81
Key words
BRD4 inhibitor,homologous recombination,PARP inhibitor,CtBP-interacting protein,CtIP
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