Bioactive sesquiterpenoids and steroids from the resinous exudates of Commiphora myrrha
Natural Product Research(2019)
摘要
Chemical investigation of the resinous exudates of Commiphora myrrha has led to the isolation of four sesquiterpenes (1a/1b, 2, and 3), including one pair of new sesquiterpene enantiomers (1a/1b), one new racemic mixture 2, and two steroids (4 and 5). Their structures were elucidated by spectroscopic analysis, and the absolute configurations of 1a/1b were determined by CD analysis. The antimigratory potential of compounds 1–5 were evaluated and compound 3 was found to inhibit human hepatocellular liver carcinoma HepG2 cell migration in dose-dependent manner.
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关键词
Commiphora myrrha,sesquiterpene,steroids,antimigratory activity
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