Direct Factor X Sequestration By Systemic Amyloid Light-Chain Amyloidosis

Haruko Tashiro,Ryosuke Shirasaki,Masato Watanabe,Kazuo Kawasugi,Yoshihisa Takahashi,Naoki Shirafuji

CLINICAL CASE REPORTS（2018）

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摘要

We present a lymphoplasmacytic lymphoma patient with Factor X (FX) deficiency. Despite the absence of FX inhibitor, the administration of fresh frozen plasma and anti-inhibitor coagulant complex did not increase the FX level. The autopsy showed that massive amyloid depositions to multiple organs and FX existed in union with amyloidosis.

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关键词

Amyloid Light-chain amyloidosis, Factor X antibody, Factor X deficiency, lymphoplasmacytic lymphoma

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