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Simultaneous quantification of free curcuminoids and their metabolites in equine plasma by LC-ESI-MS/MS.

Yongqiang Liu,Melissa Siard,Amanda Adams,Michael L Keowen, Travis K Miller,Frank Garza,Frank M Andrews,Navindra P Seeram

Journal of Pharmaceutical and Biomedical Analysis（2018）

Cited 18|Views13
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Abstract
•First validated LC–MS/MS method for detection of curcuminoid/metabolites in equine plasma.•First LC–MS/MS method for quantification of curcuminoid/metabolites in equine plasma.•First evaluation of curcuminoids/metabolites pharmacokinetics in horse.
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Key words
Curcuminoids,Metabolites,Equine,Plasma,LC–MS/MS,Pharmacokinetics
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