An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds

Jonathan Fusi,Sara Bianchi,Simona Daniele,Silvia Pellegrini,Claudia Martini,Fabio Galetta,Luca Giovannini,Ferdinando Franzoni

Biomedicine & Pharmacotherapy（2018）

引用 44|浏览23

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摘要

•Dietary antioxidants (polyphenols and berberine), SIRT1/AMPK and oxidative stress.•Evaluate direct and specific antioxidant activity.•Investigate the effect on SIRT1 expression and AMPK activation.•No statistically significant decrease in the number of viable cells was found.

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AMPK,APAB,BSA,CCL4,DMEM,DMSO,DTPA,FBS,GSH,GSSG,HRP,KMBA,mTOR,NAD+,NAMPT,PBS,PMSF,PVDF,RONS,ROS,SDS,SIN-1,SIRT1,TOSC,T-TBS

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