Urinary afamin levels are associated with the progression of diabetic nephropathy.

Yasushi Kaburagi,Eri Takahashi,Hiroshi Kajio,Shigeo Yamashita,Ritsuko Yamamoto-Honda,Tomoko Shiga,Akinori Okumura,Atsushi Goto, Yuka Fukazawa,Naoto Seki,Kazuyuki Tobe,Michihiro Matsumoto,Mitsuhiko Noda,Hiroyuki Unoki-Kubota

Diabetes Research and Clinical Practice（2019）

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摘要

•We performed urinary proteomic analysis of patients with diabetic nephropathy.•We comparatively analyzed the urinary levels of identified proteins using MRM assays.•The levels of afamin, CD44, and LAMP2 were associated with both ACR and eGFR.•Urinary afamin levels may predict the progression of diabetic nephropathy.

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关键词

2DICAL,A1AG,A1AT,A1BG,AACT,ACN,ACR,Afa/Cre,CD44,DN,FA,GO,LAMP2,LC,MRM,T2DM

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