Plasmodium Hsp40 and human Hsp70: A potential cochaperone-chaperone complex.
Molecular and Biochemical Parasitology(2017)
摘要
•The chaperoning of parasite derived proteins to the erythrocyte membrane is poorly understood.•HHsp70 interacts with the PEXEL domain containing Type II PfHsp40s but not with the Type I PfHsp40s.•PfHsp70-1 interacts with the Type I PfHsp40s but not with the PEXEL domain containing Type II PfHsp40s.•Potential chaperone-cochaperone complex of hHsp70-PfHsp40 (Type II) is likely to export parasite proteins to the RBC membrane.
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关键词
PfHsp40,PEXEL motif,hHsp70 (HSPA1A),PfHsp70-1
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