Search for More Effective Microsatellite Markers for Forensics With Next-Generation Sequencing.

Published by the Combined DNA Index System (CODIS) program of the Federal Bureau of Investigation (FBI) in 1997, the 13 core short tandem repeat (STR) loci are widely adopted as genetic markers in forensic applications, e.g., identity testing and paternity testing. However, these loci may be biased and suffer from reduced sensitivities toward specific population groups. In addition, the rapid grow...