Age-dependent decrease of GAD65/67 mRNAs but normal densities of GABAergic interneurons in the brain regions of Shank3-overexpressing manic mouse model.

Neuroscience Letters(2017)

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摘要
•The densities of PV+ and SOM+ interneurons are normal in the Shank3 transgenic mice.•The protein levels of GAD65 and GAD67 are normal in the Shank3 transgenic mice.•The mRNA levels of GAD65 and GAD67 are age-dependently decreased in the Shank3 transgenic mice.
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关键词
GAD65,GAD67,GABAergic interneuron,Parvalbumin,Shank3
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