Organ Donor Screening Practices for Strongyloides stercoralis Infection among US Organ Procurement Organizations.

TRANSPLANT INFECTIOUS DISEASE(2018)

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Abstract
BackgroundTargeted donor screening for strongyloidiasis performed at the time of organ procurement can prevent this life-threatening donor-derived infection. MethodThe Association of Organ Procurement Organizations surveyed members to determine the number of US organ procurement organizations (OPOs) performing donor screening for Strongyloides infection and their screening practices. ResultsAll 58 OPOs responded to the survey. Only 6 (10%) currently screen donors for strongyloidiasis; most OPOs started 6-36months before the survey and one started 6years prior. All used risk-based criteria to determine which donors to screen, though the criteria varied among OPOs. A median of 56 donors have been screened at each OPO since initiating their screening programs, with a median of 2 infected donors (range 0-13) identified. Overall, 53 organs have been transplanted from 22 infected donors, including hearts, lungs, kidneys, and livers. Of 52 OPOs not currently screening, 20 had considered screening and one plans to start screening in the near future. Of those considering risk-based screening, most had not decided on the criteria. Uncertainty about the benefits of and guidelines for screening and misconceptions about the interpretation of test results were concerns shared by non-screening OPOs. ConclusionContinued education and advocacy on the importance of targeted donor screening are needed.
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Key words
donor screening,donor-derived infection,parasitic infections,strongyloidiasis,transplant-associated infection
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