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Adalimumab for Corticosteroid and Infliximab-Resistant Immune Reconstitution Inflammatory Syndrome in the Setting of TB/HIV Coinfection.

Nilar Lwin,Michael Boyle,Joshua S Davis

OPEN FORUM INFECTIOUS DISEASES（2018）

Cited 13|Views4
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Abstract
Corticosteroids are the mainstay of therapy for immune reconstitution inflammatory syndrome (IRIS). However, little is known about how to treat IRIS unresponsive to steroids. We report a patient with HIV-TB coinfection who was unresponsive to first prednisolone and then infliximab but whose IRIS resolved with adalimumab.
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Key words
adalimumab,HIV,immune reconstitution,steroid,tuberculosis
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