Predicting Development of Amyotrophic Lateral Sclerosis in Frontotemporal Dementia.

Tim Van Langenhove,Olivier Piguet,James R Burrell,Cristian Leyton,David Foxe, Melissa Abela,Lauren Bartley,Woojin S Kim,Eve Jary,Yue Huang,Carol Dobson-Stone,John B Kwok,Glenda M Halliday,John R Hodges

EUROPEAN JOURNAL OF NEUROLOGY（2017）

Cited 17|Views48

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Abstract

FTD patients with a mixed bvFTD+PNFA phenotype and with a C9orf72 repeat expansion should be closely monitored for the possible development of ALS. The risk of developing ALS in FTD appears to decline with the duration of FTD symptoms.

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Key words

Amyotrophic lateral sclerosis,disease progression,frontotemporal dementia,incidence,primary progressive aphasia,prognosis

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