Functional characterization and FTIR-based 3D modeling of full length and truncated forms of Scorpio maurus venom phospholipase A.
Biochimica et Biophysica Acta (BBA) - General Subjects(2018)
摘要
•High activity of Sm-PLGV results from the excision of the penta-peptide.•The resulting short chain is important for enzymatic activity.•Hemolytic power is related to phospholipase activity.•FTIR-assisted 3D modeling showed the role of the short chain enzymatic activity.
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关键词
Sm-PLGV,rPLA2(+5),rPLA2(−5),Long chain,hbPLA2,sPLA2,p-BPB,FTIR,Egg-PC,diC12-PC,diC12-PE,PS,PG
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