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The Phosphotyrosine Phosphatase Shp2 Promotes Anergy In Chronic Lymphocytic Leukemia

Simon Schliffke,Sophia Buhs,Sarah Bolz,Helwe Gerull,Lisa von Wenserski,Kristoffer Riecken,Boris Fehse,Peter Nollau,Mascha Binder

BLOOD（2018）

Cited 3|Views19
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Abstract
TO THE EDITOR:Anergy describes a state of B-cell receptor activation that leads to survival but not to proliferation in chronic lymphocytic leukemia (CLL) cells, and a high proportion of anergic cells correlates with an indolent clinical course. To gain deeper insights into anergic and
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