In vivo effects of aspirin and cyclosporine on regulatory T cells and T-cell cytokine production in healthy dogs.

T M Archer,J V Stokes,E Kummari,C Fellman,J Thomason,J Haraschak,R Wills,L Pinchuk,A Mackin

Veterinary Immunology and Immunopathology（2018）

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摘要

•Cyclosporine significantly decreased IL-2 and IFN-γ expression.•High-dose aspirin, but not low-dose aspirin, significantly decreased IL-2 expression.•No drug or drug combination affected Treg numbers.

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关键词

IL-2,IFN-γ,Tregs,IMHA,PTE

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