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Chemokines beyond chemo-attraction: CXCL10 and its significant role in cancer and autoimmunity.

Nathan Karin,Hila Razon

Cytokine（2018）

Cited 133|Views5
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Abstract
Chemokines are mostly known for their chemotactic properties, and less for their ability to direct the biological function of target cells, including T cells. The current review focuses on a key chemokine named CXCL10 and its role in directing the migratory propertied and biological function of CD4+ and CD8+ T cells in the context of cancer and inflammatory autoimmunity.
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Key words
CXCR3,CXCL10,Chemokines,Cancer,Autoimmunity
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