Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damage.

Varvara Trachana,Spyros Petrakis, Zisis Fotiadis,Evangelia K Siska, Vasileios Balis,Efstathios S Gonos,Martha Kaloyianni,George Koliakos

Cytotherapy（2017）

引用 31|浏览11

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摘要

On the basis of these results, we propose that hTERT enhancement confers resistance to genomic damage due to the amelioration of the cell's basic antioxidant machinery.

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关键词

mesenchymal stem cells,telomerase,oxidative stress,genomic damage

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