Deep learning improves prediction of CRISPR–Cpf1 guide RNA activity

Hui Kwon Kim,Seonwoo Min,Myungjae Song,Soobin Jung,Jae Woo Choi,Younggwang Kim,Sangeun Lee,Sungroh Yoon,Hyongbum (Henry) Kim

NATURE BIOTECHNOLOGY（2018）

引用 216|浏览50

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摘要

Using deep learning to combine target sequence and chromatin accessibility data boosts the accuracy of CRISPR–Cpf1 guide RNA activity

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关键词

CRISPR-Cas9 genome editing,Genetic engineering,Machine learning,Molecular engineering,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics

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