A Novel Substrate Radiotracer for Molecular Imaging of SIRT2 Expression and Activity with Positron Emission Tomography
Molecular Imaging and Biology（2018）
Abstract
The purpose of this study was to develop a SIRT2-specific substrate-type radiotracer for non-invasive PET imaging of epigenetic regulatory processes mediated by SIRT2 in normal and disease tissues.
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Key words
SIRT2,Epigenetic Regulation,F-18,Radiotracer,Positron Emission Tomography,Brain
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