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The neurotoxin DSP-4 induces hyperalgesia in rats that is accompanied by spinal oxidative stress and cytokine production.

Jillienne C Touchette,Joshua W Little,Gerald H Wilken,Daniela Salvemini,Heather Macarthur

Neuroscience（2018）

Cited 1|Views26
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Abstract
•DSP-4 reduces norepinephrine levels in rat spinal cord.•DSP-4 induces oxidative stress and increased inflammatory cytokine levels in the spinal cord.•DSP-4 treated rats develop thermal and mechanical hypersensitivity.
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BCA,CNP,CSF,DSP-4,EDTA,EGTA,HPLC,LC,SC,TH
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