Outcomes of a large cohort of individuals with clinically ascertained high-count monoclonal B-cell lymphocytosis.

Sameer A Parikh,Kari G Chaffee,Melissa C Larson,Paul J Hampel,Timothy G Call,Wei Ding,Saad S Kenderian,Jose F Leis,Asher A Chanan-Khan,Michael J Conte,Deborah Bowen,Susan M Schwager,Susan L Slager,Curtis A Hanson,Neil E Kay,Tait D Shanafelt

Haematologica（2018）

Cited 15|Views21

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Abstract

Virtually all cases of chronic lymphocytic leukemia (CLL) are preceded by a pre-malignant condition known as monoclonal B-cell lymphocytosis (MBL).[1][1] MBL is defined as a clonal lymphoproliferative disorder with an absolute B-cell count of u003c5 × 109/L, in the absence of symptoms, organomegaly,

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